Travelers’ Diarrhea: A Comprehensive Guide for Patients


Traveling to new destinations can be an exciting adventure, but it often comes with its own set of health challenges. One of the most common health concerns faced by travelers is travelers’ diarrhea (TD). This condition can range from a mild inconvenience to a severe disruption of your travel plans. Understanding travelers’ diarrhea is crucial, especially for those visiting high-risk areas. This guide aims to provide comprehensive information about TD, from its causes and symptoms to prevention and treatment strategies.

The importance of this guide lies in its ability to empower travelers with knowledge. Being well-informed about TD can help you take preventive measures, recognize symptoms early, and seek appropriate treatment if needed. This ensures that your travel experience remains safe and enjoyable. Whether you are a seasoned traveler or planning your first international trip, this guide is an essential resource for staying healthy abroad.

Section 1: What is Travelers’ Diarrhea?

Definition and Overview

Travelers’ diarrhea is a digestive tract disorder that commonly affects travelers. It is characterized by unformed stools and is usually accompanied by other symptoms like abdominal cramps, nausea, and sometimes fever. The condition is considered the most predictable travel-related illness, with a significant impact on both leisure and business travelers.


TD is primarily caused by ingesting food or water contaminated with pathogenic microorganisms. The most common culprits include:

  • Bacteria: Such as Escherichia coli (E. coli), Campylobacter, Shigella, and Salmonella.
  • Viruses: Like norovirus and rotavirus.
  • Parasites: Including Giardia lamblia and Cryptosporidium.

Contamination can occur through poor hygiene practices in food handling, inadequate cooking, or unsafe water sources. In many cases, the organisms causing TD are part of the normal flora in the local population, which means they may not affect locals but can cause illness in travelers.

High-Risk Destinations

The risk of developing TD varies greatly depending on the travel destination. High-risk areas include:

  • Parts of Asia: Particularly South Asia and Southeast Asia.
  • Africa: Sub-Saharan and North Africa.
  • Middle East: Certain areas with lower standards of food and water hygiene.
  • Central and South America: Regions with varying levels of sanitation infrastructure.

Understanding the specific risks associated with your travel destination is vital in preparing adequately and reducing the risk of TD. This guide will further delve into how you can protect yourself in these areas and what steps to take if you develop symptoms of travelers’ diarrhea.

Section 2: Symptoms and Diagnosis of Travelers’ Diarrhea

Symptoms of Travelers’ Diarrhea

The primary symptom of travelers’ diarrhea is the sudden onset of loose or watery stools, often accompanied by other gastrointestinal symptoms. These can include:

  • Abdominal cramps and discomfort: A feeling of bloating or pain in the stomach area.
  • Urgency to defecate: Frequent trips to the bathroom with little warning.
  • Nausea and vomiting: In some cases, especially if caused by certain viruses or parasites.
  • Fever: Occurs less commonly but can be present, especially in more severe infections.
  • Loss of appetite: Along with general malaise.

The severity of symptoms can vary, with some travelers experiencing mild discomfort and others facing debilitating symptoms that can disrupt travel plans.

Diagnosis of Travelers’ Diarrhea

Travelers’ diarrhea is primarily diagnosed based on symptoms and the recent history of travel to a high-risk area. Laboratory tests are not usually required unless symptoms are severe or persistent. In such cases, stool samples may be tested to identify the specific pathogen. This can be particularly important if there are signs of a more serious infection, such as blood in the stool, prolonged fever, or dehydration.

When to See a Doctor

Medical consultation is recommended if:

  • Symptoms are severe or debilitating.
  • Diarrhea lasts longer than 48 hours.
  • There are signs of dehydration (e.g., excessive thirst, dry mouth, little or no urination).
  • There is blood or pus in the stool.
  • The traveler has a high fever or severe abdominal pain.

Section 3: Prevention Strategies

Preventing travelers’ diarrhea is largely about minimizing exposure to the pathogens that cause it. This can be achieved through careful selection and handling of food and water, and maintaining good hygiene.

Food and Water Precautions

  • Consume only bottled or purified water: Avoid tap water, including ice made from tap water.
  • Eat freshly cooked, hot foods: Heat kills most pathogens, so freshly cooked foods are usually safer.
  • Avoid raw fruits and vegetables: Unless you can peel them yourself.
  • Be cautious with street food: Choose vendors who have a high turnover of food and who cook food to order.
  • Avoid unpasteurized dairy products: These can contain harmful bacteria.

Hand Hygiene

  • Wash hands regularly: Especially before eating or preparing food and after using the bathroom.
  • Use hand sanitizer: If soap and water are not available, use an alcohol-based hand sanitizer.

Prophylactic Medications

While not routinely recommended for all travelers, prophylactic antibiotics may be considered for short trips to high-risk areas, especially for individuals at increased risk for severe disease or complications from travelers’ diarrhea. Consultation with a healthcare provider before travel is essential to evaluate the risks and benefits of prophylaxis.


There is a vaccine for cholera (which can also protect against certain types of E. coli) that might be recommended for travelers to certain areas. Travelers should consult their healthcare provider to determine if the vaccine is appropriate for their travel destination.

Section 4: Treatment Options for Travelers’ Diarrhea

Home Care and Hydration

The cornerstone of treating travelers’ diarrhea is to maintain hydration. Diarrhea can lead to significant fluid and electrolyte loss, so it’s crucial to drink plenty of fluids. Here are some guidelines:

  • Oral Rehydration Solutions (ORS): These are recommended to replenish lost electrolytes and fluids. They are available at pharmacies in most countries.
  • Clear Fluids: In addition to ORS, drinking clear broths, diluted fruit juices, and caffeine-free soft drinks can help maintain hydration.
  • Avoid Dairy Products: These can worsen diarrhea in some individuals.

Over-the-Counter Medications

  • Anti-Diarrheal Agents: Medications like loperamide (Imodium) can reduce the frequency of bowel movements and provide quick relief. They are usually safe for adults but should be used cautiously and only for short periods.
  • Bismuth Subsalicylate (Pepto-Bismol): This can decrease the duration and intensity of diarrhea but may interact with certain medications and is not suitable for everyone.

Prescription Medications

  • Antibiotics: In cases of severe or persistent diarrhea, a doctor may prescribe antibiotics. The choice of antibiotic depends on the destination, as resistance patterns vary globally.
  • Probiotics: Some evidence suggests that certain probiotics can help in managing TD, although they are not a substitute for conventional treatment.

When to Seek Medical Attention

  • If symptoms are severe (high fever, blood in stools, dehydration).
  • If symptoms persist for more than 48 hours despite treatment.
  • For individuals with underlying health conditions or those who are immunocompromised.

Section 5: Complications and Risks

Potential Complications

While most cases of travelers’ diarrhea are self-limiting, complications can occur, especially without proper treatment:

  • Dehydration: Particularly in young children and the elderly, dehydration can be severe and life-threatening.
  • Persistent Diarrhea: In a small number of cases, diarrhea can persist for weeks or even months, leading to malnutrition and significant weight loss.
  • Secondary Infections: The initial infection can sometimes lead to other complications, such as urinary tract infections or intestinal infections.

Special Considerations

  • Children: They can become dehydrated more quickly than adults. Oral rehydration solutions are particularly important, and medical advice should be sought early.
  • Pregnant Women: Certain medications for TD are not recommended during pregnancy. Pregnant women should consult with a healthcare provider for safe treatment options.
  • Chronic Illnesses: Individuals with chronic illnesses, like diabetes or heart disease, may have more complications and should consult a healthcare provider for specific advice before traveling.

Recurrence and Post-Infectious Conditions

  • Some travelers may experience a recurrence of symptoms after returning home.
  • Conditions like irritable bowel syndrome (IBS) can develop after a bout of travelers’ diarrhea, known as post-infectious IBS.

Section 6: Frequently Asked Questions (FAQs)

Q1: How Can I Prevent Travelers’ Diarrhea?

A: Prevention focuses on being cautious with food and water consumption. Drink bottled or purified water, avoid raw fruits and vegetables unless you can peel them, eat freshly cooked food, and practice good hand hygiene. In some cases, a healthcare provider may recommend prophylactic medications or vaccines for certain destinations.

Q2: What Are the Signs That My Travelers’ Diarrhea Is Severe?

A: Severe symptoms include persistent diarrhea lasting more than 48 hours, dehydration (indicated by symptoms like excessive thirst, reduced urination, lightheadedness), high fever, bloody or pus-filled stools, and severe abdominal pain. Seek medical attention if you experience these symptoms.

Q3: Are There Any Vaccines Available for Travelers’ Diarrhea?

A: There is a vaccine for cholera that also provides some protection against certain types of E. coli, a common cause of TD. This vaccine may be recommended for travel to areas where cholera is prevalent. Consult your healthcare provider for personalized advice.

Q4: Can Travelers’ Diarrhea Recur After Returning Home?

A: Yes, it’s possible for symptoms to recur or for new gastrointestinal issues like irritable bowel syndrome to develop after an episode of TD. If symptoms persist or recur after returning home, seek medical advice.

Q5: How Should I Manage My Diet If I Have Travelers’ Diarrhea?

A: Focus on staying hydrated and consume bland, easy-to-digest foods like rice, bread, bananas, and soup. Avoid dairy products, spicy foods, alcohol, and caffeinated beverages until your symptoms improve.

Section 7: Travel Tips

General Travel Health Tips

  • Visit a Travel Health Clinic: Ideally, visit a clinic 4-6 weeks before your trip for personalized health advice, vaccinations, and medications.
  • Pack a Travel Health Kit: Include items like hand sanitizer, oral rehydration salts, over-the-counter medications for diarrhea, and any prescription medications.
  • Stay Informed: Be aware of any health notices or outbreaks in your destination.


Traveling is a rewarding experience, but it comes with its own set of health risks. Being informed about travelers’ diarrhea, how to prevent it, and how to manage it if it occurs, is crucial for any traveler. With the right precautions and knowledge, you can significantly reduce your risk and ensure a more enjoyable and safe travel experience.

How can I contact gastroenterologist Dr. Zavos for an appointment?

Dr. Chris Zavos is a board-certified gastroenterologist and hepatologist, located in Thessaloniki Greece, and specifically in Kalamaria suburb, about 7 kilometres (4 miles) southeast of downtown Thessaloniki. His private office is at: Fanariou 8 street (near Aigaiou and Adrianoupoleos avenues), Kalamaria (Thessaloniki), Greece.

Thessaloniki International Airport is only 10 km away from his private office in Kalamaria and can be reached by taxi within 13 minutes from the airport.

Dr. Chris Zavos performs endoscopies at Bioclinic private hospital in downtown Thessaloniki (Mitropoleos 86 street).

You can contact Dr. Zavos at phone numbers: (+30)-6976596988 and (+30)-2311283833, or you can email him at Dr. Zavos responds to Greek and English languages.

For more information

  1. Centers for Disease Control and Prevention (CDC)
  2. CDC Yellow Book 2024
Last update: 9 April 2024, 22:33


Gastroenterologist - Hepatologist, Thessaloniki

PhD at Medical School, Aristotle University of Thessaloniki, Greece

PGDip at Universitair Medisch Centrum Utrecht, The Netherlands

Ex President, Hellenic H. pylori & Microbiota Study Group